RTG 2408 - Maladaptive processes across physiological barriers in chronic diseases

2022

Abdi Sarabi M, Shiri A, Aghapour M, Reichardt C, Brandt S, Mertens PR, Medunjanin S, Bruder D; Braun-Dullaeus RC; Weinert S. 2022. Normoxic HIF-1α stabilization caused by local inflammatory factors and its consequences in human coronary artery endothelial cells. Cells. IF: 7,666 PMID: 36497143

Aghapour M, Surender S, Bruder D. 2022. Beware the intruder: gasodermin A as molecular guardian preventing systemic dissemination of group A streptococci following local skin infection. Cell Mol Immunol. 19:761-763 IF: 22,096 PMID: 35414713

Aghapour M, Tulen CBM, Abdi Sarabi M, Weinert S, Müsken M, Relja B, van Schooten F-J, Jeron A, Braun-Dullaeus RC, Remels AH, Bruder D. 2022. Cigarette smoke extract disturbs mitochondria-regulated air-way epithelial cell responses to pneumococci. Cells. 11:1771. IF: 7,666 PMID: 35681466

Aghapour M, Ubags ND, Bruder D, Hiemstra PS, Sidhaye V, Rezaee F, Heijink IH. 2022. Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD. Eur Respir Rev. 31:210112 IF: 9,553 PMID: 35321933

Al-Dabet MM, Shahzad K, Elwakiel A, Sulaj A, Kopf S, Bock F, Gadi I, Zimmermann S, Rana R, Krishnan S, Gupta D, Manoharan J, Fatima S, Nazir S, Schwab C, Baber R, Scholz M, Geffers R, Mertens PR, Nawroth PP, Griffin JH, Keller M, Dockendorff C, Kohli S, Isermann B. 2022. Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression. Nat Commun. 13:5062. IF: 17.694 PMID: 36030260

Ambreen S, Fatima S, Elwakiel A, Rana R, Singh K, Gupta A, Gupta D, Khawaja H, Manoharan J, Besler C, Laufs U, Kohli S, Isermann B, Shahzad K. 2022. Hypercoagulability impairs plaque stability in diabetes-induced atherosclerosis. Nutrients. 14:1991. IF: 6,706 PMID:35631132

Chaithongyot S, Naumann M. 2022. Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell-death. Cell Mol Life Sci. 79:86 IF: 9,237 PMID: 35066747

Fatima S, Ambreen S, Mathew A, Elwakiel A, Gupta A, Singh K, Krishnan S, Rana R, Khawaja H, Gupta D, Manoharan J, Besler C, Laufs U, Kohli S, Isermann B, Shahzad K. 2022. ER-stress and senescence coordinately promote endothelial barrier dysfunction in diabetes-induced atherosclerosis. Nutrients. 14:2786. IF: 6,706 PMID: 35889743

Franz T, Negele J, Bruno P, Böttcher M, Mitchell-Flack M, Reemts L, Krone A, Mougiakakos D, Müller AJ, Zautner AE, Kahlfuss S. 2022. Pleiotropic effects of antibiotics on T cell metabolism and T cell-mediated immunity. Front Microbiol. IF: 6.064 PMID: 36329851

Franz T, Negele J, Kahlfuss S. 2022. Cytotoxic innate lymphoid cells sense tumor-derived IL-15: a novel mechanism of cancer immunosurveillance. Signal Transduct Target Ther. 7:326 IF: 38,126 PMID: 36115839

Gaul S, Shahzad K, Medert R, Gadi I, Mäder C, Schumacher D, Wirth A, Ambreen S, Fatima S, Boeckel JN, Khawaja H, Haas J, Brune M, Nawroth PP, Isermann B, Laufs U, Freichel M. 2022. Novel nongenetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosis. Front Cardiovasc Med. 9:813215. IF: 5.846 PMID: 35350534

Gelmez E, Jeron A, Bruder D. 2022 Negative elongation factor: a key factor in the maintenance of intestinal epithelial barrier integrity. Cell Mol Immunol. 19:453-455. IF: 22,096. PMID: 34992279

Gelmez E, Lehr K, Kershaw O, Frentzel S, Vilchez-Vargas R, Bank U, Link A, Schüler T, Jeron A, Bruder D. 2022. Characterization of maladaptive processes in acute, chronic and remission phases of experimental colitis in C57BL/6 mice. Biomedicines10:1903 IF: 4,757 PMID: 36009449

Gupta A, Singh K, Fatima S, Ambreen S, Zimmermann S, Younis R, Krishnan S, Rana R, Gadi I, Schwab C, Biemann R, Shahzad K, Rani V, Ali S, Mertens PR, Kohli S, Isermann B. 2022. Neutrophil extracellular traps promote NLRP3 inflammasome activation and glomerular endothelial dysfunction in diabetic kidney disease. Nutrients. 14:2965. IF: 6,706 PMID: 35889923

Jantaree P, Chaithongyot S, Sokolova O, Naumann M. 2022. USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection. Cell Mol Life Sci. 79:461 IF: 9,237 PMID: 35913642

Jantaree P, Yu Y, Chaithongyot S, Täger T, Abdi Sarabi M, Meyer TF, Boccellato F, Maubach G, Naumann M. 2022. Human gastric fibroblasts ameliorate A20-dependent cell survival in co-cultured gastric epithelial cells infected by Helicobacter pylori. Biochim Biophys Acta–Mol Cell Res. 1869:119364. IF: 5.011 PMID: 36162648

Krone A, Fu Y, Schreiber S, Kotrba J, Borde L, Nötzold A, Thurm C, Negele J, Franz T, Stegemann-Koniszewski S, Schreiber J, Shukla A, Geffers R, Schraven B, Reinhold D, Dudeck A, Reinhold A, Müller A, Kahlfuss S. 2022. Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc. Sci Rep. 12:1943 IF: 4,996 PMID: 35121767

Noack L, Xu B, Bundkirchen K, Zhou Y, Köhler K, Jantaree P, Neunaber C, Nowak A, Relja B. 2022. Acute intoxication with alcohol reduces trauma-induced proinflammatory response and barrier breakdown in the lung via Wnt/ß-catenin signaling pathway. Front Immunol. 13:866925 IF: 8,786 PMID: 35663960

Ragipoglu D, Bülow J, Hauff K, Voss M, Haffner-Luntzer M, Dudeck A, Ignatius A, Fischer V. 2022. Mast cells drive systemic inflammation and compromised bone repair after trauma. Front Immunol. 13:883707. IF: 8,786 PMID: 35558068

Rana R, Manoharan J, Gupta A, Gupta D, Elwakiel A, Khawaja H, Fatima S, Zimmermann S, Singh K, Ambreen S, Gadi I, Biemann R, Jiang S, Shahzad K, Kohli S, Isermann B. 2022. Activated protein C ameliorates tubular mitochondrial reactive oxygen species and inflammation in diabetic kidney disease. Nutrients. 14:3138. IF: 6,706 PMID: 35956315

Roder M, Kahlfuss S. 2022. Implementation of immunometabolism into curricula, scientific societies, and immunological routine diagnostics. J Immunological Sci. 6:18-21 LINK

Shahzad K, Fatima S, Khawaja H, Elwakiel A, Gadi I, Ambreen S, Zimmermann S, Mertens PR, Biemann R, Isermann B. 2022. Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease. Kidney Int. 102:766-779 IF: 18,998 PMID: 35779608

Wackernagel L-M, Abdi Sarabi M, Weinert S, Zuschratter W, Richter K, Fischer KD, Braun-Dullaeus R, Medunjanin S. 2022. IKKγ/NEMO localization into multivesicular bodies. Int J Mol Sci. 23:6778 IF: 6,208 PMID:35743220

Zimmermann S, Vogel M, Mathew A, Ebert T, Rana R, Jiang S, Isermann B, Biemann R. 2022. The extent of lifestyle-induced weight loss determines the risk of prediabetes and metabolic syndrome recurrence during a 5-year follow-up. Nutrients. 14:3060. IF: 6,706 PMID: 35893913

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